IMPROVED SURVIVAL IN BETA THALASSEMIA MAJOR
نویسندگان
چکیده
منابع مشابه
Endocrine Disorders in Beta thalassemia Major Patients
Background Thalassemia is the most common hereditary disorder worldwide. The patient's’ survival is dependent on lifetime blood transfusion which leads to iron overload and its toxicity on various organs including endocrine glands. The study aimed to investigate endocrine disorders in patients with Beta-thalassemia major in the Southern Khorasan province, Iran. Materials and Methods In this des...
متن کاملSurvival Analysis and its Associated Factors of Beta Thalassemia Major in Hamadan Province
Background: There currently is a lack of knowledge about the long-term survival of patients with beta thalassemia (BT), particularly in regions with low incidence of the disease. The aim of the present study was to determine the survival rate of the patients with BT major and the factors associated with the survival time.Methods: This retrospective cohort study was performed in Hamadan province...
متن کاملCytokine Gene Polymorphisms in Iranian Patients with Beta-Thalassemia Major
Background: β-thalassemia as a hereditary disease is defined as defective synthesis of β-globin chains, resulting in erythropoiesis abnormalities and severe anemia. Different studies have shown that cytokines and cytokine gene polymorphisms play a major role in the pathogenesis of β-thalassemia. Single nucleotide polymorphisms (SNPs) within the promoter region or other regulatory sequences ...
متن کاملPredicting Factors of Atherosclerosis in Children with Beta-Thalassemia Major
Background: Atherosclerosis is an important cardiovascular disorder in beta-thalassemia major patients. The present study aimed to predict factors of atherosclerosis in children with beta-thalassemia major. Materials and Methods: This cross-sectional study was conducted on 36 patients with beta-thalassemia major and 36 healthy children as the control group. The carotid intima-media thickness ...
متن کاملSerum Antioxidant Levels in Children with Beta-Thalassemia Major
Background: Thalassemia represents a serious health problem in Iran because of its heterogeneous frequency and the existing endogamy system. It is an inherited blood disease characterized by the under production of normal hemoglobin, the oxygen-carrying protein in red blood cells. Materials and Methods: In this study, serum antioxidants including selenium (Se), zinc (Zn) and copper (Cu) were m...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1987
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198704010-00789